Sequencing Methods

Detailed information can be found in our Sample and Sequencing Guidelines

Variant Detection
  • Whole Genome sequencing Sequencing of the whole genome of an organism, including coding and non-coding regions
  • Long-Read sequencing Sequencing of long inserts of DNA allowing better mapping and phasing of the genome
  • Panel sequencing In depth sequencing of a particular set of DNA regions using panels
  • Exome sequencing Sequencing of all protein coding regions of the genome of an organism
  • Targeted RNA sequencing Sequencing of a subset of transcripts enabling both qualitative and quantitative expression analysis
Expression Analysis
  • mRNA sequencing Sequencing of all messenger RNA transcripts which provides information on the whole coding transcriptome of an organism
  • Total RNA sequencing Sequencing of all types of RNAs present, including diverse small and non-coding RNAs
  • 3'-Sequencing Sequencing of transcripts 3’ UTR allowing gene expression analysis with high sensitivity and in degraded sample
  • scRNA sequencing Sequencing the RNA of individual cells to capture cell heterogeneity
  • miRNA sequencing Sequencing of micro RNAs which confer gene silencing and are often associated with various cellular mechanisms
  • smallRNA sequencing Sequencing of small RNAs (including micro RNA) which exert diverse functions of gene regulation
  • Long-Read RNA sequencing Sequencing of full-length RNA allowing precise isoform detection
Metagenomics
  • Shotgun MetagenomicsSequencing of all genomic information of a sample containing DNA of a community of organisms
  • 16S/Amplicon Sequencing Sequencing of the 16S rRNA coding region to identify different taxa in a sample containing DNA of diverse organisms
  • MetatranscriptomicsSequencing of the RNA in a heterogenous sample to analyse gene expression in a community of organisms
Epigenomics
  • Whole genome bisulfite sequencing Investigation of the methylation pattern in the whole genome of an organism
All major technologies under one roof!
Sequencers
  • Illumina NextSeq500flexible mid-output sequencer
  • Illumina MiSeqlow-output sequencer
  • Illumina NovaSeq6000production scale instrument
  • Illumina NovaSeq X Plusproven sequencer with more power
  • ONT MinIONlow throughput long read sequencer
  • ONT PromethION high throughput long-read sequencer
Sample Preparation Systems
  • Qiagen QIAcubehigh throughput isolation
  • Agilent Bravoproduction scale liquid handler
  • Qiagen QIASymphonyhigh throughput isolation
  • Tecan Fluent 780high throughput liquid handler
  • 10x Genomicssingle cell emulsion preparation
  • Beckman Biomek i5high throughput liquid handler
  • Beckman Biomek i7high throughput liquid handler